Disease Progression: Various factors that influence HBV disease progression including genotype, viral load (HBV DNA), hepatitis B “e” antigen (HBeAg) status, steatosis, obesity, insulin resistance, and general studies on disease progression.

Children

· 923. High Prevalence of HBV-DNA in Children with Chronic Hepatitis B after Seroconversion to Anti-Hbe

Development of Cirrhosis and Liver Cancer

· 820. Fusion HBx from HBV integrant in human hepatoma cell line is implicated in the development and progression of hepatocellular carcinoma

· 841. Pattern of serial HBV DNA level and HCC development in Patients with Liver Cirrhosis

· 845. Clinical Significance of Low Viral Load in Antiviral Treatment-naive HBsAg Positive Patients (Updated Nov 2)

· 847. Future Hepatitis Activation and Hepatocarcinogenesis in HBeAg-Negative HBV Carriers with Persistently Normal Alanine Aminotransferase, a Prospective Cohort Study

· 848. Rituximab Leads to Reactivation of Hepatitis B in Individuals with Resolved Infection

· 867. Accumulation of Hepatitis B Virus DNA in Hepatocellular Carcinoma of Patients with Sustained Virological Response for Hepatitis C Virus

· 982. Oncologist Compliance with Recommendations for Hepatitis B Serostatus Testing: Experience from an academic hospital.

General

· 317. Role of Viral and Clinical Factors Predicting the Outcomes of Patients with Hepatitis B Virus-Related Acute Liver Failure

Role of Genotypes and Mutations

· 818. Reactive Oxygen Species Induce Liver Fibrosis in uPA/SCID Mice with Human Hepatocytes Infected with Specific Hepatitis B Virus Genotypes

· 851. Influences of Hepatitis B Virus Genotype and Precore Mutations on Reactivation of Occult Hepatitis B in Patients with Hematological Malignancy

· 863. Drifting of HBV-specific CTL Epitope HBcAg18-27V to HBcAg18-27I in Most HBV Genotype B and C Virus Strains in China

· 864. Large Deletion Mutants of Hepatitis B Virus with Amino Acid Substitutions in the Core Region Emerges and Dominates Around the Onset of Active Hepatitis in Persistent HBV Carriers

· 868. Increasing Frequency of Acute Hepatitis B with Imported Strain Genotype A in Japan

· 869. Non-A Hepatitis B Genotypes are Associated with More Liver Fibrosis in HIV/HBV Patients

· 870. Higher Levels of HBV-DNA in Genotypes B and C Compared to Genotypes A and D

· 871. The Frequency of T126 in Surface Antigen Increase with Disease Progression in Patients with Chronic Hepatitis B Virus (Genotype C) Infection

· 872. Mechanism for the Dependence of Hepatitis B Virus Genotypes G on Coinfection with Other Genotypes for Viral Replication

· 989. Precore (PC) and Basic Core Promoter (BCP) Mutations and Genotypes in Relation to Viral Replication in Asymptomatic HBsAg-Positive Blood Donors in Greece

Role of HBeAg Status

· 815. Age-specific Prognosis Following HBeAg Seroconversion in Chronic Hepatitis B

· 829. Evolution of HBV Quasipecies Generates New CpG Dinucleotides Prior to HBeAg Seroconversion

· 838. Histological Findings Of HBeAg-negative Chronic HBV -Infected Patients With Persistently Normal Serum Alanine Aminotransferase Levels

· 861. Hepatitis B Viral Factors Influencing the Histological Changes Of HBeAg-negative Chronic HBV Infected Patients With Persistently Normal Serum Alanine Aminotransferase Levels

· 862. Hepatitis B Virus Basal Core Promoter Mutation and DNA Load Correlate with Expression of Hepatitis B Core Antigen

Viral Replication and Integration

· 816. Cleavage of Duck Hepatitis B Virus Envelope Protein by Endosomal Proprotein Convertase Promotes Viral cccDNA Formation in Non-susceptible LMH Cells

· 817. HBx Protein Is Necessary for HBV Replication in Human Hepatocytes

· 819. Mechanism of Hepatitis B Virus Persistence Following an Acute Infection – A study using duck hepatitis B virus of the roles of virus replication and cell turnover.

· 822. Cytopathic Effect of Hepatitis B Virus Obtained from Fulminant Hepatitis Patients

· 825. Increased Innate and Adaptive Immune Pressure Is Responsible for the Reduced Transcriptional Activity of Intrahepatic Covalently-Closed Circular (ccc) DNA That Occurs in HBeAg-negative Chronic Hepatitis B (CHB)

· 828. Cellular Immune Response to Recombinant Surface and Core HBV Antigens Is Not Impaired in Blood Donors with Occult Hepatitis B Infection

· 831. High Prevalence of Hepatic Steatosis and its Impact on Fibrosis in Chronic Hepatitis B

· 832. RIG-I signaling Expression in Monocyte-derived Dendritic Cells in Patients with Hepatitis B virus infection

· 833. Hepatitis B virus-replication could induce sHSP60 and enhance regulatory T cell activity via toll like receptor 2

· 834. T-1993C Polymorphism in The Promoter of TBX21 Gene Is Associated With Susceptibility to Persistent Hepatitis B Virus Infection

· 835. A previously unidentified subset of CD4-CD8-T cells contributes to the persistence of chronic viral hepatitis via virus specific killing of CD8+ T cells

· 837. Intrahepatic Analysis of Cytokine and Toll-like Receptor Signaling Expression in Chronic Hepatitis B Patients with Different HBV Replicative Activity

· 843. Genetic Variability on the cccDNA Regulatory Regions Changes Significantly in the Different Phases of Chronic HBV Infection

· 844. Single nucleotide polymorphisms and functional analysis of Class II transactivator (CIITA) coding region in chronic HBV infection

· 849. Control of HBV Replication by HepaRG cells Innate Response

· 854. Plasmacytoid Dendritic Cell Function Is Impaired in Chronic Hepatitis B Infection

· 856. Viral Hepatitis B Virus (HBV) Promotes Extracellular Matrix Disruption Promoted by Viral Transactovatpr X (HBx) and Mediated by Gelatinase A.

· 857. Modulation of Human Hepatic Stellate Cells (HSCS) Behavior by Hepatitis B Virus (HBV) X Protein (HBX) Through Transforming Growth Factor Beta Signalling Pathway

· 858. High HBV DNA Load, HBeAg Positivity and Considerable Hepatic Necro Inflammation in Patients with Incidentally Detected, Asymptomatic Chronic HBV-infected Individuals from Bangladesh

· 859. Lack of Correlation Between Viral Load and Extent of Liver Damage in Patients with Chronic HBV Infection in Bangladesh

· 860. Modulation of ERK, AKT, apoptosis and cell cycle in primary mouse hepatocytes and Huh7 cells by wild-type and rtM204I HBV.

· 855. Assessment of Delta and Hepatitis B Viremia in Patients with Chronic Hepatitis Delta. Influence of HIV Infection and Antiviral Therapy.